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human transcriptome array (hta) microarray platform  (Thermo Fisher)


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    Structured Review

    Thermo Fisher human transcriptome array (hta) microarray platform
    Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the <t>transcriptomes</t> across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.
    Human Transcriptome Array (Hta) Microarray Platform, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+transcriptome+array+(hta)+microarray+platform/pmc06246735-48-13-12
    Average 90 stars, based on 1 article reviews
    human transcriptome array (hta) microarray platform - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures"

    Article Title: Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures

    Journal: Frontiers in Microbiology

    doi: 10.3389/fmicb.2018.02685

    Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the transcriptomes across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.
    Figure Legend Snippet: Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the transcriptomes across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.

    Techniques Used:

    Related Articles

    other:

    Article Title: Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures
    Article Snippet: Gene microarrays for the infected and control hNEC samples were performed using Affymetrix human transcriptome array (HTA) microarray platform.

    Article Title: Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
    Article Snippet: Gene expression and alternative splicing microarray was performed using the Affymetrix platform GeneChip Human Transcriptome array 2.0 (HTA 2.0) ( ) containing a median of 10 probes per exon or ncRNA and 4 probes per junction (> 6.0 million distinct probes in total covering coding and non-coding transcript) .

    Gene Expression:

    Article Title: Transcriptome analysis identifies putative multi-gene signature distinguishing benign and malignant pancreatic head mass
    Article Snippet: .. Gene expression profiling was done by microarray using Affymetrix human transcriptome array 2.0 (HTA 2.0) platform, which consists of probes for both coding and non-coding genes. cDNA was prepared from ~ 10 μg of RNA, biotinylated according to standard Affymetrix protocol and then hybridized onto Affymetrix HTA 2.0 Arrays for overnight in the hybridization oven and then the array chips were washed and stained in the Affymetrix Fluidics Station 450. .. GeneChips were scanned using the Affymetrix GeneChip® Scanner 3000 7G and raw files were obtained as CEL files.

    Microarray:

    Article Title: Transcriptome analysis identifies putative multi-gene signature distinguishing benign and malignant pancreatic head mass
    Article Snippet: .. Gene expression profiling was done by microarray using Affymetrix human transcriptome array 2.0 (HTA 2.0) platform, which consists of probes for both coding and non-coding genes. cDNA was prepared from ~ 10 μg of RNA, biotinylated according to standard Affymetrix protocol and then hybridized onto Affymetrix HTA 2.0 Arrays for overnight in the hybridization oven and then the array chips were washed and stained in the Affymetrix Fluidics Station 450. .. GeneChips were scanned using the Affymetrix GeneChip® Scanner 3000 7G and raw files were obtained as CEL files.

    Article Title: RCAN1-4 is a thyroid cancer growth and metastasis suppressor
    Article Snippet: .. To investigate the effects of RCAN1-4 knockdown in tumor cells on gene transcription, microarray analysis was performed using the Affymetrix Human Transcriptome Array 2.0 (HTA 2.0) platform with RNA isolated from shCtrl and shRCAN1-4 cells for the FTC236 and HTh74 cell lines. ..

    Article Title: Molecular Interplay between Dormant Bone Marrow-Resident Cells (BMRCs) and CTCs in Breast Cancer
    Article Snippet: .. Microarray hybridization was performed using the Human Transcriptome Array 2.0 (HTA_2.0) platform (Affymetrix, Santa Clara, CA, USA). .. Files were normalized and analyzed by Transcriptome Analysis Console, version 4.0.1 (Affymetrix).

    Hybridization:

    Article Title: Transcriptome analysis identifies putative multi-gene signature distinguishing benign and malignant pancreatic head mass
    Article Snippet: .. Gene expression profiling was done by microarray using Affymetrix human transcriptome array 2.0 (HTA 2.0) platform, which consists of probes for both coding and non-coding genes. cDNA was prepared from ~ 10 μg of RNA, biotinylated according to standard Affymetrix protocol and then hybridized onto Affymetrix HTA 2.0 Arrays for overnight in the hybridization oven and then the array chips were washed and stained in the Affymetrix Fluidics Station 450. .. GeneChips were scanned using the Affymetrix GeneChip® Scanner 3000 7G and raw files were obtained as CEL files.

    Article Title: Molecular Interplay between Dormant Bone Marrow-Resident Cells (BMRCs) and CTCs in Breast Cancer
    Article Snippet: .. Microarray hybridization was performed using the Human Transcriptome Array 2.0 (HTA_2.0) platform (Affymetrix, Santa Clara, CA, USA). .. Files were normalized and analyzed by Transcriptome Analysis Console, version 4.0.1 (Affymetrix).

    Staining:

    Article Title: Transcriptome analysis identifies putative multi-gene signature distinguishing benign and malignant pancreatic head mass
    Article Snippet: .. Gene expression profiling was done by microarray using Affymetrix human transcriptome array 2.0 (HTA 2.0) platform, which consists of probes for both coding and non-coding genes. cDNA was prepared from ~ 10 μg of RNA, biotinylated according to standard Affymetrix protocol and then hybridized onto Affymetrix HTA 2.0 Arrays for overnight in the hybridization oven and then the array chips were washed and stained in the Affymetrix Fluidics Station 450. .. GeneChips were scanned using the Affymetrix GeneChip® Scanner 3000 7G and raw files were obtained as CEL files.

    Knockdown:

    Article Title: RCAN1-4 is a thyroid cancer growth and metastasis suppressor
    Article Snippet: .. To investigate the effects of RCAN1-4 knockdown in tumor cells on gene transcription, microarray analysis was performed using the Affymetrix Human Transcriptome Array 2.0 (HTA 2.0) platform with RNA isolated from shCtrl and shRCAN1-4 cells for the FTC236 and HTh74 cell lines. ..

    Isolation:

    Article Title: RCAN1-4 is a thyroid cancer growth and metastasis suppressor
    Article Snippet: .. To investigate the effects of RCAN1-4 knockdown in tumor cells on gene transcription, microarray analysis was performed using the Affymetrix Human Transcriptome Array 2.0 (HTA 2.0) platform with RNA isolated from shCtrl and shRCAN1-4 cells for the FTC236 and HTh74 cell lines. ..



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    human transcriptome array (hta) microarray platform  (Thermo Fisher)
    90
    Thermo Fisher human transcriptome array (hta) microarray platform
    Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the <t>transcriptomes</t> across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.
    Human Transcriptome Array (Hta) Microarray Platform, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+transcriptome+array+(hta)+microarray+platform/pmc06246735-48-13-12
    Average 90 stars, based on 1 article reviews
    human transcriptome array (hta) microarray platform - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the transcriptomes across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.

    Journal: Frontiers in Microbiology

    Article Title: Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures

    doi: 10.3389/fmicb.2018.02685

    Figure Lengend Snippet: Individual heat-map and PCA analysis of five individual subjects show similar trends but potentially retained some degree of variability in temporal induction and magnitude between donors. (A) Individual heat-maps of different subjects revealed largely similar patterns with potential differences in temporal induction from 8 to 48 hpi, including the magnitude of induction. (B) Individual PCA plot showed that the transcriptomes across different subjects were not clustered as tightly since the hNEC samples were of different genetic backgrounds. The PCA plot showed a distinct progression of differential gene changes across time-points even at 0 hpi. (C) Individual viral titers increased over time to reach high viral loads in samples from all donors. The individual variation was deemed not clinically significant given that a sufficiently high virus titer was attained to induce a consistent response.

    Article Snippet: Gene microarrays for the infected and control hNEC samples were performed using Affymetrix human transcriptome array (HTA) microarray platform.

    Techniques: